Study With Me : Introduction to Blood Transfusion 4
SECTION 1 : Haematology
Questions & Answers
Erythropoiesis Questions and Answers
Question 30: What is erythropoiesis?
Erythropoiesis is the process of red blood cell production in the body.
Question 31: How does a sudden substantial loss of blood affect erythropoiesis?
A sudden substantial loss of blood dramatically increases erythropoiesis to replace the lost red blood cells.
Question 32: Why might an individual become anemic over a long period of time without obvious symptoms?
Gradual and regular loss of red blood cells over time may lead to anemia without noticeable symptoms until the hemoglobin level becomes dangerously low.
Question 33: What is the primary factor controlling the rate of red blood cell production?
The oxygen content of the blood is the major factor controlling the rate of red blood cell production.
Question 34: What condition is associated with a low blood oxygen level?
A low blood oxygen level is associated with hypoxia.
Question 35: What is hypoxia, and how does it relate to erythropoiesis?
Hypoxia is a condition of low tissue oxygen. Hypoxia is the strongest stimulus for erythropoiesis, especially seen in individuals living at high altitudes where there is less oxygen in the air.
Question 36: How does hypoxia influence the production of red blood cells?
Hypoxia causes the release of erythropoietin, a hormone produced in the kidneys, which stimulates the bone marrow to produce more red blood cells.
Question 37: What is the role of erythropoietin in erythropoiesis?
Erythropoietin stimulates erythrocyte-forming cells in the bone marrow to differentiate, divide, and eventually form mature red blood cells.
Question 38: What are reticulocytes?
Reticulocytes are immature red blood cells.
Question 39: How does erythropoietin affect the release of reticulocytes into the circulation?
Erythropoietin causes the release of reticulocytes into the circulation.
Question 40: What is the outcome of an increased red cell mass?
An increased red cell mass results in more hemoglobin available to deliver oxygen to tissues.