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Study With Me : Introduction to Blood Transfusion 33
Study With Me : Introduction to Blood Transfusion 33

Study With Me : Introduction to Blood Transfusion 33

Study With Me : Introduction to Blood Transfusion 33

SECTION 1 : Haematology

Questions and Answers

Medical Questions and Answers

Question 179:

What distinguishes thalassaemia major from thalassaemia minor?

Answer: Thalassaemia major is a more severe form, often transfusion-dependent, causing enlargement of the liver and spleen, and bone expansion.

Question 180:

What is sickle cell anaemia, and what causes it?

Answer: Sickle cell anaemia is an inherited disorder seen in the Arabian Peninsula, Asia, and Africa, caused by a structural defect in the beta-globin chain of the haemoglobin molecule, leading to the formation of HbS and haemolysis.

Question 181:

What happens during a sickle cell crisis?

Answer: During a sickle cell crisis, red cells change into a sickle or crescent shape, can become lodged in capillaries, and have a decreased lifespan.

Question 182:

In sickle cell anaemia, when is transfusion necessary?

Answer: Transfusion may be necessary in sickle cell anaemia cases where routine transfusion helps lower the concentration of HbS.

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