Study With Me : Introduction to Blood Transfusion 32
SECTION 1 : Haematology
Questions and Answers
What is the origin of platelets (thrombocytes)?
Answer: Platelets originate from the cytoplasm of bone marrow cells called megakaryocytes.
What is the role of platelets in blood coagulation?
Answer: Platelets participate in blood coagulation by forming a plug to seal damaged blood vessels, crucial for haemostasis.
What are reticulocytes, and how are they identified in the bloodstream?
Answer: Reticulocytes are immature red cells with remnants of the cell nucleus. They are identified in the bloodstream by their elevated number, particularly in anaemic individuals.
What are the red cell abnormalities associated with chronic anaemia?
Answer: Red cell abnormalities leading to chronic anaemia include thalassaemia and sickle cell anaemia.
What is thalassaemia, and what causes it?
Answer: Thalassaemia is an inherited disorder, primarily in Asia and the Eastern Mediterranean, caused by a quantitative abnormality in the alpha or beta-globin chain in the haemoglobin molecule, leading to shortened red cell lifespan.